[4-(trifluoromethyl)phenyl]methylammonium
4-(trifluoromethyl)benzylamine
CAS: 3300-51-4
Molecular Formula: C8H8F3N
[4-(trifluoromethyl)phenyl]methylammonium - Names and Identifiers
| Name | 4-(trifluoromethyl)benzylamine |
| Synonyms | p-CF3-benzylamine 4-Trifluoromethylbenzylamine 4-(trifluoromethyl)benzylamine 4-(Trifluoromethyl)benzenemethanamine 1-[4-(trifluoromethyl)phenyl]methanamine [4-(trifluoromethyl)phenyl]methanaminium [4-(trifluoromethyl)phenyl]methylammonium 4-(Aminomethyl)benzotrifluoride, [4-(Trifluoromethyl)phenyl]methylamine 4-Aminomethylbenzotrifluoridealpha-Amino-alpha',alpha',alpha'-trifluoro-p-xylene |
| CAS | 3300-51-4 |
| EINECS | 221-971-9 |
| InChI | InChI=1/C8H8F3N/c9-8(10,11)7-3-1-6(5-12)2-4-7/h1-4H,5,12H2/p+1 |
[4-(trifluoromethyl)phenyl]methylammonium - Physico-chemical Properties
| Molecular Formula | C8H8F3N |
| Molar Mass | 175.15 |
| Density | 1.229 g/mL at 25 °C (lit.) |
| Melting Point | 43 °C |
| Boling Point | 79-82 °C (15 mmHg) |
| Flash Point | 167°F |
| Vapor Presure | 0.526mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.229 |
| Color | Clear colorless to light yellow |
| BRN | 2640698 |
| pKa | 8.60±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.464(lit.) |
[4-(trifluoromethyl)phenyl]methylammonium - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 2735 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Note | Corrosive |
| Hazard Class | 8 |
| Packing Group | III |
[4-(trifluoromethyl)phenyl]methylammonium - Reference Information
| Uses | 4-(trifluoromethyl) benzylamine is an organic intermediate, which can be obtained by reducing amination from trifluoromethyl benzaldehyde. There are reports that it can be used to prepare a medicament for controlling plant fungi in the field of agriculture or forestry. |
| preparation | in the reactor, 15kg of distilled water, 2.50kg of sodium acetate, 2.30kg of hydroxylamine hydrochloride and 4.00kg of methanol are added. At room temperature, 5.0kg of trifluoromethylbenzaldehyde was added, and the mixture was first stirred for three ten minutes, and then 5kg of solvent was distilled under vacuum. Subsequently, 12.0kg of 80% acetic acid was added and 4.5kg of zinc was added in subsequent fractions, so that the temperature rose to 60-80°C due to heat release. Subsequently, this temperature is maintained by cooling. At the end of this reaction, 10.0kg of toluene and 15.0kg of 30% ammonia were added to remove the zinc salt. The obtained substance was stirred at 50-60°C and the aqueous phase of the underlying layer was subsequently removed. 4.00kg of 4-(trifluoromethyl) benzylamine was obtained as determined by potentiometric titrator. Yield: 79.5%. |
Last Update：2024-04-09 20:52:54
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